genetic mutation

noun

plural genetic mutations
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.Natalie Angier

Examples of genetic mutation in a Sentence

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But only a fraction of children with the genetic mutation actually develop autism, Miller said. Liz Szabo, NBC News, 22 Nov. 2024 Seventy-nine of the food-processing chemicals found in the body are known to cause cancer, genetic mutations, endocrine and reproductive issues, and other health concerns, according to the study published Monday in the Journal of Exposure Science & Environmental Epidemiology. Sandee Lamotte, CNN, 16 Sep. 2024 Often persistent, the lesions can result from genetic mutations, chronic irritation, or exposure to risk factors like tobacco, alcohol, or HPV infection. Dan Perry, Newsweek, 31 Jan. 2025 Viral samples from a patient in Louisiana who was hospitalized with severe H5N1 avian influenza show genetic mutations that could make the pathogen spread more easily among humans, the Centers for Disease Control and Prevention announced in a statement issued on Thursday. Tanya Lewis, Scientific American, 27 Dec. 2024 See All Example Sentences for genetic mutation

Word History

First Known Use

1915, in the meaning defined above

Time Traveler
The first known use of genetic mutation was in 1915

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Cite this Entry

“Genetic mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genetic%20mutation. Accessed 3 Mar. 2025.

Medical Definition

genetic mutation

noun
: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes
Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.Joseph Alper
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